scientificpublications

Scientific Publications 2024

sara.marchetti1@unimib.it Pubblicazioni, Research
  • Tseberlidis G., Trifiletti V., Husien A.H., L’Altrella A., Binetti S, Gosetti F. Cu2ZnSnS4 Nanoparticles as an Efficient Photocatalyst for the Degradation of Diclofenac in Water. Appl. Sci. 2024, 14, 9923. DOI: 10.3390/app14219923
  • Gualtieri M, Melzi G, Costabile F, Stracquadanio M, La Torretta T, Di Iulio G, Petralia E, Rinaldi M, Paglione M, Decesari S, Mantecca P, Corsini E. On the dose-response association of fine and ultrafine particles in an urban atmosphere: toxicological outcomes on bronchial cells at realistic doses of exposure at the Air Liquid Interface. Chemosphere. 2024 Sep 28:366:143417. DOI: 10.1016/j.chemosphere.2024.143417
  • Marchetti S, Colombo A, Saibene M, Bragato C, La Torretta T, Rizzi C, Gualtieri M, Paride Mantecca P. Shedding light on the cellular mechanisms involved in the combined adverse effects of fine particulate matter and SARS-CoV-2 on human lung cells. Sci Total Environ. 2024 Nov 20:952:175979. DOI: 10.1016/j.scitotenv.2024.175979
  • Botto L, Bulbarelli A, Lonati E, Cazzaniga E, Palestini P. Correlation between Exposure to UFP and ACE/ACE2 Pathway: Looking for Possible Involvement in COVID-19 Pandemic. Toxics. 2024 Jul 31;12(8):560. DOI: 10.3390/toxics12080560
  • Bragato C, Persico A, Ferreres G, Tzanov T, Mantecca P. Exploring the Effects of Lignin Nanoparticles in Different Zebrafish Inflammatory Models. Int J Nanomedicine. 2024 Jul 30:19:7731-7750. DOI: 10.2147/IJN.S469813
  • Furxhi I, Perucca M, Koivisto AJ, Bengalli R, Mantecca P, Nicosia A, Burrueco-Subirà D, Vázquez-Campos S, Lahive E, Blosi M, Lopez de Ipiña  J, Oliveira J, Carriere M, Vineis C, Costa A. A roadmap towards safe and sustainable by design nanotechnology: Implementation for nano-silver-based antimicrobial textile coatings production by ASINA project. Comput Struct Biotechnol J. 2024 Jun 15:25:127-142. DOI: 10.1016/j.csbj.2024.06.013
  • Bragato C, Mazzotta R, Persico A, Bengalli R, Ornelas M, Gomes F, Bonfanti P, Mantecca P. Biocompatibility Analysis of Bio-Based and Synthetic Silica Nanoparticles during Early Zebrafish Development. Int J Mol Sci. 2024 May 18;25(10):5530. DOI: 10.3390/ijms25105530
  • Saibene M, Serchi T, Bonfanti P, Colombo A, Nelissen I, Halder R, Audinot JN, Pelaz B, Soliman MG, Parak WJ, Mantecca P, Gutleb AC, Cambier S. The use of a complex tetra-culture alveolar model to study the biological effects induced by gold nanoparticles with different physicochemical properties. Environ Toxicol Pharmacol. 2024 Mar:106:104353. DOI: 10.1016/j.etap.2023.104353
  • Perelshtein I, Shoshani S, Jacobi G, Natan M,  Dudchenko N, Perkas N, Tkachev M, Bengalli R, Fiandra L, Mantecca P, Ivanova K, Tzanov T, Banin E, Gedanken A. Protecting the Antibacterial Coating of Urinal Catheters for Improving Safety. ACS Appl Bio Mater. 2024 Feb 19;7(2):990-998. DOI: 10.1021/acsabm.3c00988
  • Motta G, Gualtieri M, Bengalli R, Saibene M, Belosi F, Nicosia A, Cabellos J, Mantecca P. An integrated new approach methodology for inhalation risk assessment of safe and sustainable by design nanomaterials. Environ Int. 2024 Jan:183:108420. DOI: 10.1016/j.envint.2024.108420

Scientific Publications 2023

sara.marchetti1@unimib.it Publications, Research
  • Bengalli RD, Zerbi G, Lucotti A, Catelani T, Mantecca P. Carbon nanotubes: Structural defects as stressors inducing lung cell toxicity. Chem Biol Interact. 2023 Sep 1;382:110613. https://doi.org/10.1016/j.cbi.2023.110613
  • Botto L, Lonati E, Russo S, Cazzaniga E, Bulbarelli A, Palestini P. Effects of PM2.5 Exposure on the ACE/ACE2 Pathway: Possible Implication in COVID-19 Pandemic. Int J Environ Res Public Health. 2023 Mar 1;20(5):4393. https://doi.org/10.3390/ijerph20054393
  • Bragato C, Pistocchi A, Bellipanni G, Confalonieri S, Balciunie J, Monastra FM, Carra S, Vitale G, Mantecca P, Cotelli F, Gaudenzi G. Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue. J Neurosci Res. 2023 Apr 9. https://doi.org/1002/jnr.25197.
  • Gualtieri M, Carriere M, Mantecca P. Hazard, Distribution and Exposure of Particulate Pollution from Indoor and Outdoor Environments.Toxics. 2023 Sep 12;11(9):772. https://doi.org/10.3390/toxics11090772
  • Kose O, Béal D, Motellier S, Pelissier N, Collin-Faure V, Blosi M, Bengalli R, Costa A, Furxhi I, Mantecca P, Carriere M. Physicochemical Transformations of Silver Nanoparticles in the Oro-Gastrointestinal Tract Mildly Affect Their Toxicity to Intestinal Cells In Vitro: An AOP-Oriented Testing Approach. Toxics. 2023; 11(3):199. https://doi.org/10.3390/toxics11030199
  • Kose O, Mantecca P, Costa A, Carrière M. Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review. Part Fibre Toxicol. 2023 Jan 5;20(1):1. https://doi.org/1186/s12989-022-00511-9
  • Marchetti S., Gualtieri M., Pozzer A, Lelieveld J., Hansell A. L., Colombo A., Mantecca P. On fine particulate matter and COVID-19 spread and severity: an in vitro toxicological plausible mechanism. Environ Int. 179 (2023) 108131. https://doi.org/10.1016/j.envint.2023.108131
  • Moschini E, Colombo G, Chirico G, Capitani G, Dalle-Donne I, Mantecca P. Biological mechanism of cell oxidative stress and death during short-term exposure to nano CuO. Sci Rep. 2023 Feb 9;13(1):2326. https://doi.org/1038/s41598-023-28958-6
  • Motta G, Gualtieri M, Saibene M, Bengalli R, Brigliadori A, Carrière M, Mantecca P. Preliminary Toxicological Analysis in a Safe-by-Design and Adverse Outcome Pathway-Driven Approach on Different Silver Nanoparticles: Assessment of Acute Responses in A549 Cells. Toxics. 2023; 11(2):195. https://doi.org/10.3390/toxics11020195

New Article published!

sara.marchetti1@unimib.it News and Events, Publications , ,
New Article published!

What is the connection between pollution and COVID19?

The POLARIS “Health and Environmental Sustainability” Research Centre has demonstrated how air pollution can play a crucial role in the transmission of the SARS-CoV-2 virus and the resulting severity of the COVID-19 disease. The study, recently published in the journal Environment International, paves the way for a greater understanding of how atmospheric particulate matter can influence and facilitate the possibility of contracting respiratory diseases transmitted by viruses or bacteria and provides fundamental information to understand how the population responds to the same threat depending on the quality of the environment in which it lives.

To find out more, read the interview with our researchers, edited by the press office of the University of Milan-Bicocca.

Further information on Environment International:

Marchetti S, Gualtieri M, Pozzer A, Lelieveld J, Saliu F, Hansell AL, Colombo A, Mantecca P. On fine particulate matter and COVID-19 spread and severity: An in vitro toxicological plausible mechanism.

 

Scientific Publications 2022

sara.marchetti1@unimib.it Publications, Research
  • Bengalli B, Zerboni A, Bonfanti P, Saibene M, Mehn D, Cella C, Ponti J, La Spina R, Mantecca P. Characterization of microparticles derived from waste plastics and their bio-interaction with human lung A549 cells. J Appl Toxicol. 2022 Dec;42(12):2030-2044. doi: 10.1002/jat.4372. Epub 2022 Aug 30. https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jat.4372
  • Bonfanti P, Colombo A, Saibene M, Motta G, Saliu F, Catelani T, Mehn D, La Spina R, Ponti J, Cella C, Floris P, Mantecca P. Microplastics from miscellaneous plastic wastes: Physico-chemical characterization and impact on fish and amphibian development. Ecotoxicol Environ Saf. 2021 Dec 1;225:112775. doi: 10.1016/j.ecoenv.2021.112775. Epub 2021 Sep 15. https://www.sciencedirect.com/science/article/pii/S0147651321008873
  • Bragato C, Mostoni S, D’Abramo C, Gualtieri M, Pomilla FR, Scotti R, Mantecca P. On the In Vitro and In Vivo Hazard Assessment of a Novel Nanomaterial to Reduce the Use of Zinc Oxide in the Rubber Vulcanization Process. Toxics. 2022; 10(12):781. https://doi.org/10.3390/toxics10120781
  • Ferrero L, Scibetta L, Markuszewski P, Mazurkiewicz M, Drozdowska V, Makuch P, Jutrzenka-Trzebiatowska P, Zaleska-Medynska A, Andò S, Saliu F, Nilsson E. D, Bolzacchini E. Airborne and marine microplastics from an oceanographic survey at the Baltic Sea: An emerging role of air-sea interaction? Sci Total Environ. 2022 Jun 10;824:153709. doi: 10.1016/j.scitotenv.2022.153709. Epub 2022 Feb 9. https://pubmed.ncbi.nlm.nih.gov/35150686/
  • Ivanova A, Ivanova K, Fiandra L, Mantecca P, Catelani T, Natan M, Banin E, Jacobi G, Tzanov T. Antibacterial, Antibiofilm, and Antiviral Farnesol-Containing Nanoparticles Prevent Staphylococcus aureus from Drug Resistance Development. Int J Mol Sci. 2022 Jul 7;23(14):7527. doi: 10.3390/ijms23147527. https://www.mdpi.com/1422-0067/23/14/7527
  • Massimino L, Bulbarelli A, Corsetto P. A, Milani C, Botto L, Farina F, Lamparelli L. A, Lonati E, Ungaro F, Maddipati K. R, Palestini P, Rizzo A. M. LSEA Evaluation of Lipid Mediators of Inflammation in Lung and Cortex of Mice Exposed to Diesel Air Pollution. Biomedicines. 2022 Mar 19;10(3):712. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945792/
  • Perucca, M.; Capuano, L.; Magatti, G.; Rosa, F.; Mantecca, P. Environmental Performance of Road Asphalts Modified with End-of-Life Hard Plastics and Graphene: Strategies for Improving Sustainability. Processes 2022, 10, 2151. https://doi.org/10.3390/pr10102151
  • Traina G, Bolzacchini E, Bonini M, Contini D, Mantecca P, Caimmi S. M. E, Licari A. Role of air pollutants mediated oxidative stress in respiratory diseases. Pediatr Allergy Immunol. 2022 Jan;33 Suppl 27(Suppl 27):38-40. https://pubmed.ncbi.nlm.nih.gov/35080317/
  • Zerboni A, Rossi T, Bengalli R, Catelani T, Rizzi C, Priola M, Casadei S, Mantecca P. Diesel exhaust particulate emissions and in vitro toxicity from Euro 3 and Euro 6 vehicles. Environ Pollut. 2022 Mar 15;297:118767. https://www.sciencedirect.com/science/article/pii/S0269749121023496?via%3Dihub

Scientific Publications 2021

sara.marchetti1@unimib.it Publications, Research, Scientific Publications Archive
  • Bengalli R, Fiandra L, Vineis C, Sanchez-Ramirez DO, Azoia NG, Varesano A, Mantecca P. Safety Assessment of Polypyrrole Nanoparticles and Spray-Coated Textiles. Nanomaterials (Basel).2021 Aug 3;11(8):1991. https://doi.org/10.3390/nano11081991
  • Bengalli R, Colantuoni A, Perelshtein I, Gedanken A, Collini M, Mantecca P, Fiandra L. In vitro skin toxicity of CuO and ZnO nanoparticles: Application in the safety assessment of antimicrobial coated textiles. 2021 Jan;21:100282. doi: 10.1016/j.impact.2020.100282. Epub 2020 Dec 7. https://doi.org/10.1016/j.impact.2020.100282
  • Bertero A, Colombo G, Cortinovis C, Bassi V, Moschini E, Bellitto N, Perego MC, Albonico M, Astori E, Dalle-Donne I, Gedanken A, Perelshtein I, Mantecca P, Caloni F. In vitro copper oxide nanoparticle toxicity on intestinal barrier. J Appl Toxicol. 2021 Feb;41(2):291-302. https://doi.org/10.1002/jat.4047
  • Bonfanti P, Colombo A, Saibene M, Motta G, Saliu F, Catelani T, Mehn D, La Spina R, Ponti J, Cella C, Floris P, Mantecca P. Microplastics from miscellaneous plastic wastes: Physico-chemical characterization and impact on fish and amphibian development. Ecotoxicol Environ Saf. 2021 Dec 1;225:112775. https://doi.org/10.1016/j.ecoenv.2021.112775
  • Botto L, Bulbarelli A, Lonati E, Cazzaniga E, Tassotti M, Mena P, Del Rio D, Palestini P. Study of the Antioxidant Effects of Coffee Phenolic Metabolites on C6 Glioma Cells Exposed to Diesel Exhaust Particles. Antioxidants (Basel). 2021 Jul 23;10(8):1169. https://doi.org/10.3390/antiox10081169
  • Deokar AR, Perelshtein I, Saibene M, Perkas N, Mantecca P, Nitzan Y, Gedanken A. Antibacterial and In Vivo Studies of a Green, One-Pot Preparation of Copper/Zinc Oxide Nanoparticle-Coated Bandages. Membranes (Basel). 2021 Jun 22;11(7):462. https://doi.org/10.3390/membranes11070462
  • Floris P, Garbujo S, Rolla G, Giustra M, Salvioni L, Catelani T, Colombo M, Mantecca P, Fiandra L. The Role of Polymeric Coatings for a Safe-by-Design Development of Biomedical Gold Nanoparticles Assessed in Zebrafish Embryo. Nanomaterials (Basel). 2021 Apr 14;11(4):1004. https://doi.org/10.3390/nano11041004
  • Furxhi I, Bengalli R, Motta G, Mantecca P, Kose O, Carriere M, Haq EU, O’Mahony C, Blosi M, Gardini D, Costa A. Data-Driven Quantitative Intrinsic Hazard Criteria for Nanoproduct Development in a Safe-by-Design Paradigm: A Case Study of Silver Nanoforms. ACS Appl Nano Mater. 2023 Feb 16;6(5):3948-3962. doi: 10.1021/acsanm.3c00173. eCollection 2023 Mar 10. https:// org/10.1021/acsanm.3c00173
  • Kose O, Béal D, Motellier S, Pelissier N, Collin-Faure V, Blosi M, Bengalli R, Costa A, Furxhi I, Mantecca P, Carriere M. Physicochemical Transformations of Silver Nanoparticles in the Oro-Gastrointestinal Tract Mildly Affect Their Toxicity to Intestinal Cells In Vitro: An AOP-Oriented Testing Approach. Toxics. 2023 Feb 21;11(3):199. https://doi.org/10.3390/toxics11030199
  • Marchetti S., Mollerup S., Gutzkow K. B., Rizzi C., Skuland T., Refsnes M., Colombo A., Øvrevik J, Mantecca P., Holme J. A. “Biological effects of combustion-derived particles from different biomass sources on human bronchial epithelial cells” Toxicol in Vitro 2021 May 5;105190. https://doi.org/10.1016/j.tiv.2021.105190
  • Marchetti S., Bengalli R., Floris P., Colombo A., Mantecca P. “Combustion-derived particles from biomass sources differently promote epithelial to mesenchymal transition on A549 cells” Arch Toxicol. 2021, Jan 22. https://doi.org/10.1007/s00204-021-02983-8
  • Pacitto A, Stabile L, Morawska L, Nyarku M, Torkmahalleh MA, Akhmetvaliyeva Z, Andrade A, Dominski FH, Mantecca P, Shetaya WH, Mazaheri M, Jayaratne R, Marchetti S, Hassan SK, El-Mekawy A, Mohamed EF, Canale L, Frattolillo A, Buonanno G.Daily submicron particle doses received by populations living in different low- and middle-income countries. Environ Pollut. 2021 Jan 15;269:116229.https://doi.org/10.1016/j.envpol.2020.116229
  • Zerboni A, Bengalli R, Fiandra L, Catelani T, Mantecca P. Cellular Mechanisms Involved in the Combined Toxic Effects of Diesel Exhaust and Metal Oxide Nanoparticles. Nanomaterials (Basel). 2021, May 29;11(6):1437.https://doi.org/10.3390/nano11061437

Scientific Publications 2020

sara.marchetti1@unimib.it Publications, Research, Scientific Publications Archive
  • Bonfanti P, Colombo A, Saibene M, Fiandra L, Armenia I, Gamberoni F, Gornati R, Bernardini G, Mantecca P. Iron nanoparticle bio-interactions evaluated in Xenopus laevis embryos, a model for studying the safety of ingested nanoparticles. Nanotoxicology. 2020 Mar;14(2):196-213. https://doi.org/10.1080/17435390.2019.1685695
  • Borgese M, Rossi F, Bonfanti P, Colombo A, Mantecca P, Valdatta L, Bernardini G, Gornati R. Recovery ability of human adipose stem cells exposed to cobalt nanoparticles: outcome of dissolution. Nanomedicine (Lond). 2020 Feb;15(5):453-465. https://doi.org/10.2217/nnm-2019-0195
  • Comunian S, Dongo D, Milani C, Palestini P. Air Pollution and Covid-19: The Role of Particulate Matter in the Spread and Increase of Covid-19’s Morbidity and Mortality. Int J Environ Res Public Health. 2020 Jun 22;17(12):4487. https://doi.org/10.3390/ijerph17124487
  • Longhin EM, Mantecca P, Gualtieri M.Fifteen Years of Airborne Particulates in Vitro Toxicology in Milano: Lessons and Perspectives Learned. Int J Mol Sci. 2020 Apr 3;21(7):2489. https://doi.org/10.3390/ijms21072489
  • Milani C, Farina F, Botto L, Massimino L, Lonati E, Donzelli E, Ballarini E, Crippa L, Marmiroli P, Bulbarelli A, Palestini P. Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset. Int J Mol Sci. 2020 May 24;21(10):3699. https://doi.org/10.3390/ijms21103699
  • Traina G, Barbalace A, Betti F, Bolzacchini E, Bonini M, Contini D, Felice G, Foti T, Mantecca P. What impact of air pollution in pediatric respiratory allergic diseases. Pediatr Allergy Immunol. 2020 Nov;31 Suppl 26:26-28. https://doi.org/10.1111/pai.13362