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Post-doctoral position available!

Project Title: New Integrated Methodological Approaches for the Assessment of the Safety and Environmental Sustainability of Advanced Nanostructured Materials

The procedure, based on titles and examinations, is called for the award of no. 1 Research Grant for cooperation in research activities, with a duration of 12 months, in the field of Environmental science (SDS BIO/06), for the following activities: evaluation of the toxic effects of new advanced nanomaterials using in vitro and in vivo biological models alternative to the use of mammals (zebrafish); development and application of new nanospecific characterization factors for determining the human and environmental hazard in LCA (Life Cycle Assessment) applications; implementation of quantitative methodologies in the Safe and Sustainable by Design (SSbD) framework for new advanced materials.

The position will be based at the University of Milano-Bicocca (Milan, Italy)

The position is well suited to a recent doctoral graduate with skills and interests in nanosafety and environmental impacts of new advanced materials, to sustain the SSbD framework.

The research is within the EU project INTEGRANO (Multidimensional Integrated Quantitative Approach to Assess Safety and Sustainability of Nanomaterials in Real Case Life Cycle Scenarios Using Nanospecific Impact Categories), HORIZON CL 4 2023 RESILIENCE 01 22 (GA n 101138414).

Supervisor: Paride Mantecca (paride.mantecca@unimib.it)

Application deadline: 12:00 on 30/1/2025.

Please visit the Calls for Application section to get more information.

New PhD position available!

Project title: New approach methodologies to assess the biological safety and mechanisms of action of advanced (nano)materials

The project will develop new advanced in vitro models of the lung barrier, exposed at the air-liquid-interface (ALI) with dedicated systems, to better mimicking the physiological conditions of exposure and responses to airborne particles and molecules. The new biological systems, based on the interplay of lung epithelial, endothelial and/or immune cells, also in combination with a 3D bio-printed extracellular matrix will be used to implement an adverse outcomes pathways (AOPs)-based approach to characterize the cytotoxic and proinflammatory effects of new nano(bio)materials and airborne pollutants. The project aims at establishing New Approach Methodologies (NAMs) combining advanced exposure systems, complex predictive biological models and molecular/omics, coupled with morphological approaches. A strong scientific contribution is expected in the fields of environmental toxicology and health and safety assessment of new chemicals and materials.

The PhD project is within the EU project INTEGRANO (Multidimensional Integrated Quantitative Approach to Assess Safety and Sustainability of Nanomaterials in Real Case Life Cycle Scenarios Using Nanospecific Impact Categories), HORIZON CL 4 2023 RESILIENCE 01 22 (GA n 101138414).

Tutor: Paride Mantecca

Supervisors: Maurizio Gualtieri, Laura Russo

The selection for admission to the 40th cycle PhD programme in Converging Technologies for Biomolecular Systems (UNIMIB) is open.

Please visit the Calls for Application section to get more information.