research

INTEGRANO

sara.marchetti1@unimib.it Research Projects ,
INTEGRANO

The Safe and Sustainable by Design (SSbD) framework aims to steer the innovation process towards the green and sustainable industrial transition, substitute or minimise the production and use of substances of concern, and minimise the impact on health, climate and the environment during sourcing, production, use and end-of-life of chemicals, materials and products. However, SSbD implementation to nanomaterials (NMs) is hampered by a lack of harmonized or specific data and datasets which poses a challenge to the design of safe and sustainable NMs and their incorporation into nano-enabled products (NEPs).

INTEGRANO aims to:

• Support decision making in NM development, enabling stakeholders (scientists, material engineers, policymakers) to tackle the SSbD challenge in the NM context

• Promote the design and redesign of NMs and NEPs by reducing R&D and approval lead time, minimising costs and increasing data transparency

• To support industry by reducing research and technological development and innovation risk related to safety and sustainability by enabling impact-based informed investment decisions

UNIMIB is project coordinator of the project and leader of WP3, which aims at nano-tox and nano eco-tox data generation.

Call: HORIZON-CL4-2023-RESILIENCE-01-22

Grant Agreement: 101138414

Project Coordinator: Paride Mantecca (UNIMIB)

UNIMIB WP leader: Maurizio Gualtieri (WP3 Leader)

Further information can be found at the link

MUSA

sara.marchetti1@unimib.it Air quality and health, Research Projects , , ,
MUSA

Multilayered Urban Sustainability Action

MUSA – Multilayered Urban Sustainability Action is an Innovation Ecosystem funded by the Ministry of University and Research under the National Recovery and Resilience Plan.

The project involves collaboration between the University of Milan-Bicocca, the proposing institution, the Polytechnic University of Milan, Bocconi University, Milan University and numerous public and private partners.

MUSA was established in Milan as a response to the challenges that the metropolitan city faces in the transition to the three domains of sustainability: environmental, economic and social. And with an ambition: to usher in a new model of public/private collaboration that can be replicated nationally and internationally.

MUSA identifies the Lombardy region as an ideal laboratory for testing integrated innovations and planning interdisciplinary responses that act on several city management fronts: the environmental front, in which urban development must respect and strengthen biodiversity and foster optimal solutions for energy and sustainable mobility, the technological front, with the untapped potential of digitalisation and deep tech, and the economic and financial front, in which education and sustainable finance are playing increasingly central roles.

The POLARIS Interdepartmental Research Centre is involved in the Spoke 1 of the project, dedicated to safeguarding and enhancing the potential of the natural environment within the city, from biodiversity to renewable energy sources, from monitoring to involving citizens in sustainable mobility.

Spoke Leader: Massimo Labra

Further information can be found at the link

SAMANTA

sara.marchetti1@unimib.it Research Projects , ,

SA.MA.NT.A – ScAling-up di un sisteMA aNTi-particolato, anti-coronavirus, biocida Autorigenerante

The SA.MA.NT.A project is a scaling-up innovation of a filtration system capable of retaining the totality of particulate matter with diameter greater than 4nm (inorganic, organic, and biological PM) and providing >99.99% filtration efficiency, suitable for any indoor environment.

The system allows the inactivation of COVID-19 and a general biocidal action against all biological elements. It is indeed based on a heat treatment for the inactivation of COVID-19 virus and for the combustion of all particulate material collected on the filter, resulting in a completely biocidal as well as self-healing action of the filter itself, eliminating the production of special waste.

The system is designed to be independent from all possible variants of COVID-19 and any possible future pandemic biota, being the system based on a universal method of inactivation and destruction of any biological structure based on carbon chemistry (thermal method with the possibility of acting up to 900°C).

Project Coordinator: Luca Ferrero

INTEGRANO

sara.marchetti1@unimib.it News and Events, Research ,
INTEGRANO

UNIMIB is coordinator of a new Horizon Europe project: INTEGRANO (GA. 101138414).

In line with the current guidelines for Safe and Sustainable by Design – SSbD chemicals and materials, INTEGRANO proposes a general assessment approach based on quantitative evidence to be applied in practice for specific Nano Materials (NMs) design cases.
INTEGRANO ambition is to set the basis for a new paradigm based on standardised frameworks and by creating suitable NMs datasets as well as Nanospecific impact categories of NMs through their Life Cycle Stages (LCS), applied to specific design cases assessment.

12 partners from 8 different countries participate in the Integrano Project. This network allows for different expertises and skills within the project, which complement and support each other.

For further information visit INTEGRANO page, the website INTEGRANO – INTEGRANO or the Linkedin page.

AMYGING

sara.marchetti1@unimib.it Research Projects , ,
AMYGING

AMYGING – Holistically sustainable multi-modal β-amyloid imaging

AMYGING will demonstrate in a zebrafish embryo model that natural polyphenol-based carrier systems hold great potential as natural actives useful to form the basis of a highly modular amyloid imaging toolbox suitable for in vivo MRI and difference-fluorescence imaging.

Out-of-the-box approaches for combining traditional amyloid-sensing structures with insights from nanotechnology, molecular electronics and inherent characteristics of natural polyphenols allow for the simultaneous realization of multimodal imaging probes.

AMYGING aims at the implementation of a screening platform for highly sensitive detection of misfolded Aβ-oligomers in the cerebrospinal fluid of Alzheimer’s Disease patients via tunable nanoparticles (NPs). These NPs comprise a core of natural condensed polyphenolic (PNPs) structure complexing gadolinium ions and an outer layer of PNPs that are functionalized with amyloid-sensing small actives (ASSAs), a combination which leads to effectively increased contrast agent concentration in the immediate proximity of Aβ-oligomers for optimum bimodal imaging.

Call: PRIN2022

Grant Agreement: 202295845T

Project Coordinator: Margherita Brindisi (UNINA)

UNIMIB WP leader: Heiko Lange (WP2 Leader), Anita Colombo (WP3 Leader)

IT-BEST

sara.marchetti1@unimib.it Research Projects , ,
IT-BEST

IT-BEST project aims to characterise the formation, the atmospheric ageing and the toxicological effects of ultrafine particles (UFP) resulting from the combustion of biofuels. Indeed, combustion processes involving biofuels may emit UFP that are actually different in size, chemical composition and health effects than those from conventional fossil fuels.

The special interest in UFP is related to evidence, currently available in the literature, that biofuels reduce the total particulate matter emitted, but simultaneously produce smaller particle size with a relevant number concentration, which are potentially more toxic.

Experimental measurements using an atmospheric simulation chamber, will be performed to determine the effect of different biofuels composition, on UFP numbers, size, chemical composition and their transformation under relevant atmospheric conditions as well as their toxicological assessment.

The expected outcome of the research project will result in a better the understanding of different nature and health-related toxicological effects of the carbonaceous particle formed during the combustion of biofuels.

Call: PRIN2022

Grant Agreement: 2022CH87SA

Project Coordinator: Dario Massabò (UNIGE) and Gianluigi De Falco (UNINA Federico II)

UNIMIB WP leader: Maurizio Gualtieri

BIOMAT

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BIOMAT

BIOMAT – Open  Innovation Test Bed for Nano-Enabled Bio-Based PUR Foams and composites

The POLARIS Research Center is involved in the European BIOMAT project, funded by the European Commission in the Horizon 2020 framework (Grant Agreement nr.) with the aim of establishing an Open Innovation Test Bed (BIOMAT-TB) with a Single-Entry Point (SEP) . The aim of this project is to accelerate a sustainable European bioeconomy through the development of nanomaterial-based and advanced polyurethane foams (PUR Foams) for various companies (building, construction, automotive, furniture, textiles).

Project ID:953270; Call ID: H2020-EU.2.1.3. – INDUSTRIAL LEADERSHIP – Leadership in enabling and industrial technologies – Advanced materials;   H2020-EU.2.1.2. – INDUSTRIAL LEADERSHIP – Leadership in enabling and industrial technologies – Nanotechnologies

Project coordinator: Dr. Mariana Ornelas (CENTI)

Dissemination Manager: Dr. Pnina Dan (OSM-DAN LTD).

Partner UNIMIB – POLARIS Prof. Paride Mantecca is leader of WP7 – Recycling technologies, nanosafety and regulatory issues with specific focus on Nanosafety and toxicology (Task 7.2).

Further information can be found at the link.

Discover more on the project here!

 

Research

sara.marchetti1@unimib.it Research
Research

The Interdepartmental Research Centre called “Environmental Health and Sustainability – POLARIS” aims to increase and integrate the state of knowledge in the following macro-areas of research:

AIR QUALITY AND HEALTH

Monitoring of air quality in indoor and outdoor environments and study of the impact on human and environmental health, with focus on the presence of air contaminants and the spread of pathogens.

Recent Projects:

MUSA
IT-BEST

To find out more, visit the dedicated page

INNOVATIVE, SAFE AND SUSTAINABLE TECHNOLOGIES

Support for the development of safe, sustainable and innovative (nano)technologies, with assessment of their safety during the entire life cycle (circularity). Study of emerging contaminants, their impact on health and risk prevention and mitigation strategies.

Recent Projects:

INTEGRANO
AMYGIN

To find out more, visit the dedicated page

ENVIRONMENTAL ECONOMICS AND SOCIOLOGY

Evaluation of the environmental, economic and social impacts of products and processes; development of environmental policies with a view to sustainability and circularity.

Recent Projects:

To find out more, visit the dedicated page